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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CADPS2 All Species: 31.82
Human Site: Y1164 Identified Species: 70
UniProt: Q86UW7 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86UW7 NP_001009571.2 1296 147735 Y1164 T V K A A A K Y V D V P K P G
Chimpanzee Pan troglodytes XP_001146490 1296 147661 Y1164 T V K A A A K Y V D V P K P G
Rhesus Macaque Macaca mulatta XP_001084178 1297 147885 Y1165 T V K A A A K Y V D V P K P G
Dog Lupus familis XP_532534 1204 137239 Y1073 T V K A A A K Y V D V P K P G
Cat Felis silvestris
Mouse Mus musculus Q8BYR5 1297 147822 Y1165 T V K A A A K Y V D V P K P G
Rat Rattus norvegicus Q62717 1289 146248 Y1155 T V K A A S K Y V D V P K P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507532 1359 153617 Y1227 T V K A A A K Y V D V P K P G
Chicken Gallus gallus XP_001233823 1325 150564 Y1191 T V K A A S K Y V D V P K P G
Frog Xenopus laevis Q6GLR7 1299 148702 F1165 E G T L F S S F L S F T K P G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NHE5 1436 162680 K1267 T N V S S S G K D L G Q G Y V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q23658 1396 159184 F1256 A P K P A S I F N K L K T M A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.3 88.4 N.A. 95.9 77 N.A. 85.3 77.6 77.1 N.A. N.A. 53.7 N.A. 44.7 N.A.
Protein Similarity: 100 100 99.4 90.4 N.A. 98.1 86.7 N.A. 90.1 87.6 87.7 N.A. N.A. 68.8 N.A. 63.3 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. 100 93.3 20 N.A. N.A. 6.6 N.A. 13.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 40 N.A. N.A. 26.6 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 73 82 55 0 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 73 0 0 0 0 0 % D
% Glu: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 10 0 0 19 0 0 10 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 10 0 0 0 10 0 10 0 82 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 82 0 0 0 73 10 0 10 0 10 82 0 0 % K
% Leu: 0 0 0 10 0 0 0 0 10 10 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 10 0 10 0 0 0 0 0 0 0 73 0 82 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 10 10 46 10 0 0 10 0 0 0 0 0 % S
% Thr: 82 0 10 0 0 0 0 0 0 0 0 10 10 0 0 % T
% Val: 0 73 10 0 0 0 0 0 73 0 73 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 73 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _